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Evidence-based guideline update: Vagus nerve stimulation for the
treatment of epilepsy: Report of the Guideline Development
Subcommittee of the American Academy of Neurology
George L. Morris III, David Gloss, Jeffrey Buchhalter, et al.
Neurology published online August 28, 2013
DOI 10.1212/WNL.0b013e3182a393d1
This information is current as of August 28, 2013
The online version of this article, along with updated information and services, is
located on the World Wide Web at:
/content/early/2013/08/28/WNL.0b013e3182a393d1.full.html
Neurology ® is the official journal of the American Academy of Neurology. Published continuously
since 1951, it is now a weekly with 48 issues per year. Copyright © 2013 American Academy of
Neurology. All rights reserved. Print ISSN: 0028-3878. Online ISSN: 1526-632X.
Published Ahead of Print on August 28, 2013 as 10.1212/WNL.0b013e3182a393d1
SPECIAL ARTICLE
Evidence-based guideline update: Vagus nerve
stimulation for the treatment of epilepsy
Report of the Guideline Development Subcommittee of the
American Academy of Neurology
George L. Morris III, ABSTRACT
MD, FAAN Objective: To evaluate the evidence since the 1999 assessment regarding efficacy and safety of
David Gloss, MD vagus nerve stimulation (VNS) for epilepsy, currently approved as adjunctive therapy for partial-onset
Jeffrey Buchhalter, MD, seizures in patients .12 years.
FAAN
Methods: We reviewed the literature and identified relevant published studies. We classified these
Kenneth J. Mack, MD,
studies according to the American Academy of Neurology evidence-ba
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