探讨术前给予羟考酮对瑞芬太尼快通道麻醉行腹腔镜胆囊切除术后苏醒期的影响.docVIP

探讨术前给予羟考酮对瑞芬太尼快通道麻醉行腹腔镜胆囊切除术后苏醒期的影响 　　【摘要】 目的：探讨研究给予羟考酮对瑞芬太尼快通道麻醉行腹腔镜胆囊切除术后苏醒的影响。方法：选择腹腔镜胆囊切除患者80例，将其分为对照组和观察组，对照组患者在术前20 min静脉注射0.9%氯化钠注射液，观察组在术前20 min静脉注射羟考酮，观察并记录两组患者停药后自主呼吸恢复、睁眼、拔管、睫毛反射时间及疼痛、躁动、镇静评分。结果：两组患者自主呼吸恢复、睁眼、拔管、睫毛反射时间比较差异均无统计学意义（P0.05）；在对比疼痛、躁动评分方面，观察组明显低于对照组，但观察组镇静评分高于对照组，比较差异均有统计学意义（P0.05）。结论：术前给予羟考酮镇痛可有效减轻患者苏醒期的疼痛，稳定患者生命体征。 　　【关键词】 羟考酮； 瑞芬太尼； 腹腔镜胆囊切除术； 苏醒期 　　中图分类号 R575.6 文献标识码 A 文章编号 1674-6805（2015）30-0008-02 　　【Abstract】 Objective：To study the effect of giving Oxycodone to laparoscopic cholecystectomy which be with remifentanil fast track anesthesia after in recovery.Method：80 patients undergoing laparosopic cholecystectomy were divided into two groups randomly，the control group was injected with 0.9% sodium chloride in 20 minutes before operation，the treatment group was injected Oxycodone in 20 minutes before operation.The time of two groups in discontinuation of spontaneous breathing recovery，eye opening，extubation，eyelash reflex and the score of the pain，restlessness，sedation were observed and recorded.Result：The time of patients of two groups in spontaneous breathing recovery，open and tube drawing and eyelash reflex were no difference（P0.05）.In the comparison of pain， restlessness score，the treatment group was significantly lower than the control group，but the treatment group sedation score was higher than the control group，there was statistical significance（P0.05）.Conclusion：Be giving Oxycodone analgesia before operation can effectively ease the pain of waking period in patients with stable vital signs. 　　【Key words】 Oxycodone； Rumifentanil； Laparoscopic cholecystectomy； Awakening period 　　First-author’s address：Nanjing People’s Hospital of Lishui District，Nanjing 211200，China 　　doi：10.14033/j.cnki.cfmr.2015.30.004 　　术前镇痛是指在疼痛刺激发生前给予患者进行镇痛措施，从而减轻或者消除疼痛向中枢神经系统的传递，从而发挥术后镇痛效果，降低术后并发症发生率[1]。本文对术前给予羟考酮对瑞芬太尼快速通道麻醉的腹腔镜胆囊切除术患者麻醉苏醒期间的影响进行研究分析，现报告如下。 　　1 资料与方法 　　1.1 一般资料 　　选择笔者所在医院2014年1月-2015年1月收治的行腹腔镜胆囊切除术患者80例，其中男46例，女34例；年龄23～60岁，平均（48.5±2