柴胡疏肝散治疗反流性食管炎82例疗效观察.docVIP

柴胡疏肝散治疗反流性食管炎82例疗效观察 　　[摘要] 目的 探讨并观察柴胡疏肝散治疗反流性食管炎的临床疗效。 方法 选择2008年5月～2013年5月在我院治疗的反流性食管炎患者82例，口服柴胡疏肝散治疗，作为治疗组，另取同期74例反流性食管炎患者，口服奥美拉唑肠溶胶囊联合枸橼酸莫沙必利片治疗，作为对照组，两组患者均治疗6个月，并随访3个月。观察两组患者的胃镜检查，临床症状，不良反应等情况，判定疗效。 结果 两组患者均无明显的不良反应；治疗组胃镜检查的总有效率为89.0%，对照组胃镜检查的总有效率为63.0%，差异有统计学意义（P0.05）。治疗组临床治愈44例，显效24例，有效8例，无效6例，总有效率为92.7%，对照组临床治愈26例，显效16例，有效11例，无效21例，总有效率为71.6%。差异有统计学意义（P0.05）。 结论 柴胡疏肝散治疗反流性食管炎治疗效果显著，无明显的不良反应，安全可靠，值得临床推广应用。 　　[关键词] 柴胡疏肝散；反流性食管炎；临床疗效；安全性 　　[中图分类号] R259 [文献标识码] B [文章编号] 2095-0616（2015）14-26-03 　　Observation of curative effect of Chaihu Shugan powder treatment of reflux esophagitis in 82 cases 　　JI Yanhua 　　Lindian Town Health Center of Lindian County in Daqing City， Heilongjiang， Lindian 166300， China 　　[Abstract] Objective To study the clinical effect of Chaihu Shugan powder in the treatment of reflux esophagitis. Methods 82 patients with reflux esophagitis who were treated with persral Chaihu Shugan powder in the hospital from May 2008 to May 2013 were selected as the treatment group， at the same time， 74 patients with reflux esophagitis were treated with persral omeprazole enteric-coated capsules combined mosapride citrate pills as the control group， the two groups were all treated with 6 months and 3 months follow-up. To comparatively observe the gastroscopy， the clinical symptoms， and the adverse reaction and so on， to determine the efficacy. Results There was no obviously adverse reaction of the two groups. The total effective rate of gastroscopy was 89.0% in treatment group， while which was 63.0% in control group， the difference had statistical significance（P0.05）. The total effective rate of clinical symptoms was 92.7% with cure in 44 cases， marked effect in 24 cases， effective in 8 cases， and ineffective in 6 cases in treatment group， while which was 71.6% with cure in 26 cases， marked effect in 16 cases， effective in 11 cases， and ineffective in 21 cases in control group， the difference had statistical significance （P0.05）. Conclusion Chaihu Sh