慢性心衰病人的心率变异性分析AnalysisofHeartRateVariabilityin.PDFVIP

Vol. 6 No.4/ Aug. 2012 慢性心衰病人的心率变异性分析 Analysis of Heart Rate Variability in Congestive Heart Failure 李开士 周妮娜 郑卓远 李烨 摘 要  在本文中，我们主要讨论了心率变异性的时域计算方法以及心衰病人的心率变异性变化。性别和年龄是心率变异 性的影响因素，我们发现这两种因素对于正常人和心衰病人有不同的影响方式。心衰病人的所有时域心率变异性指标相对 于正常人会显著的降低，并且随着病情的加重，SDNN和SDANN两个指标仍然会有显著的降低。我们还借助心率变异性讨 论了心衰病人昼夜节律的变化。为了更好的表示昼夜节律，我们提出了一个表示昼夜节律的综合指标。 关键词  心率变异性；心衰；昼夜节律 ABSTRACT In this paper, we mainly discussed the calculation of heart rate variability (HRV) in time domain and analyzed the change of HRV of congestive heart failure patients. Through various calculation and comparison, we proposed a new index which can be directly used to represent the HRV with variation of sleep/awake cycle. We also discussed the role of age and gender on the heart rate variability of heart failure. KEYWORDS heart rate variability; heart failure; sleep/awake cycle 1 Introduction ongestive heart failure [1], or heart failure, is a and gender. If their role isn’t clarified, the precision of Ccomplex clinical syndrome that can result from prediction of heart failure by heart rate variability will be any structural or functional cardiac disorder that impairs limited. Some large-scale experiments[4], [6], [7], [11], [12], [14] the ability of the ventricle to fill with or eject blood. The have been carried out to prove the impact of other factors most obvious symptoms of heart failure are dyspnea, (i.e., age and gender) on normal subjects, but those on fatigue, and fluid retention, which may lead to pulmonary heart failure patients are seldom discussed in literature. congestion and peripheral edema. Heart failure can By comparing with normal subjects, we test the impact severely damage patients’ physical and mental heal