神经电生理检查对危重病性神经肌病诊断意义.docVIP

神经电生理检查对危重病性神经肌病诊断意义 　　[摘要]目的 探讨神经电生理检查对危重病性神经肌病的诊断意义。方法 选取2015年1月～2016年12月我院收治的30例确诊为危重病性神经肌病患者设置为观察组，再在同时间段内选取50例体检正常者作为对照组，两组受检者均接受神经电生理检查，并对其运动神经和感觉神经电生理检查结果进行分析和比较，计算神经电生理检查对危重病性神经肌病的诊断符合情况。结果 运动神经电生理检查结果显示，观察组正中神经、尺神经的运动神经传导速度、诱发电位振幅均明显低于对照组（P0.05），其运动神经诱发电位远端潜伏期明显延长（P0.05）；感觉神经电生理检查结果显示，观察组正中神经、尺神经的感觉神经传导速度、诱发电位振幅均明显低于对照组（P0.05）；神经电生理检查对危重病性神经肌病的诊断敏感性、特异性、准确性、阳性预测值、阴性预测值分别为96.67%、96.00%、96.25%、93.55%、97.96%，与确诊结果之间的一致性良好（Kappa=0.724）。结论 神经电生理检查对危重病性神经肌病进行诊断的准确性较高，可反映危重病性神经肌病的神经损伤情况。 　　[关键词]危重病性神经肌病；神经电生理；诊断 　　[中图分类号] R746.9 [文献标识码] A [文章编号] 1674-4721（2017）05（a）-0045-03 　　[Abstract]Objective To investigate the diagnostic significance of nerve electrophysiological examination in critically illness myopathy.Methods 30 cases with critically illness myopathy diagnosed treated in our hospital from January 2015 to December 2016 were selected and set as the observation group，at the same period of time，50 healthy subjects were selected and set as control group，subjects in two groups were given electrophysiological examination，and the motor nerve and sensory nerve electrophysiological examination results were analyzed and compared，and the compliance of electrophysiological examination in diagnosis of critical illness myopathy was counted.Results The electrophysiological examination results of motor nerve showed that motor nerve conduction velocity and evoked potential amplitude of median nerve and ulnar nerve in observation group were significantly lower than those of the control group （P0.05），and distal latency of the motor evoked potential was significantly prolonged （P0.05）.The electrophysiological examination results of sense nerve showed that sense nerve conduction velocity and evoked potential amplitude of median nerve and ulnar nerve in observation group were significantly lower than those of the control group （P0.05）.The sensitivity，specificity，accuracy，positive predictive value and negative predictive value of electrophysiological examination for the diag