选择性最高的选择性5-HT再摄取抑制剂西酞普兰.docVIP

选择性最高的选择性5-HT再摄取抑制剂——西酞普兰 蒋淑莲 综述 （中南大学湘雅医学院附二医院 长沙 410011） 摘要：西酞普兰（喜普妙）是选择性最强的5-HT再摄取抑制剂（SSRI），对其他递质、受体和酶的影响小，因而具有更好的安全性和耐受性，老年患者尤为适用。本文综述了西酞普兰的的药理学特征和抗抑郁作用。 关键词：西酞普兰，抗抑郁作用。 The most selective serotonin reuptake inhibitor—citalopram Jiang Shulian Abstract: Citalopram is the most selective serotonin reuptake inhibitor with a very fewer side effects profile, it is well tolerated in all age groups, especially in elderly. This article reviews the character of citalopram in pharmacokinetics, pharmacodynamics and clinical effect on treating depression. Keywords: citalopram, antidepression