连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的比较研究.docVIP

连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的比较研究 　　摘要：目的 开展连续性肾脏替代治疗与间歇性血液透析治疗对照研究，评估不同治疗方法在重症急性肾衰治疗中的应用价值。方法 将我院2012年3月～2016年3月收治的146例重症急性肾衰患者随机分成采用连续性肾脏替代治疗的观察组与应用间歇性血液透析治疗的对照组，组间比较治疗前后患者血清肌酐（Scr）、尿素氮（BUN）、?壬?肌酐（Ccr）各项指标水平。结果 治疗前两组Scr、BUN、Ccr各项指标差异无统计学意义，治疗后观察组除Ccr指标高于对照组外，Scr与BUN指标均明显低于对照组，差异具备统计学意义（P0.05）。结论 连续性肾脏替代疗法与间歇性血液透析疗法均是治疗重症急性肾衰的有效方法，但就治疗效果来看，连续性肾脏替代疗法更具优势。 　　关键词：连续性肾脏替代；间歇性血液透析；重症急性肾衰 　　中图分类号：R692.5 文献标识码：A 文章编号：1006-1959（2017）16-0064-02 　　Comparative Study of Continuous Renal Replacement Therapy and Intermittent Hemodialysis in Treatment of Severe Acute Renal Failure 　　ZHANG Cheng-cheng 　　（Armed Police Zhejiang Province Corps Hangzhou Hospital ICU，Hangzhou 310051，Zhejiang，China） 　　Abstract：Objective Comparative study of continuous renal replacement therapy and intermittent hemodialysis treatment was conducted to evaluate the value of different treatment methods in the treatment of severe acute renal failure.Methods 146 patients with severe acute renal failure who were treated in our hospital from March 2012 to March 2016 were randomly divided into two groups：the observation group with continuous renal replacement therapy and the control group with intermittent hemodialysis.The levels of serum creatinine（Scr），urea nitrogen（BUN）and endogenous creatinine（Ccr）were compared between groups before and after treatment.Results The scores of Scr，BUN and Ccr in the two groups before treatment were not statistically significant.After treatment，the observation group except the Ccr index is higher than the control group，the Scr and BUN indicators are significantly lower than the control group，the difference has statistical significance（P0.05）.Conclusion Continuous renal replacement therapy and intermittent hemodialysis therapy are effective in the treatment of severe acute renal failure，but in terms of therapeutic effectiveness，continuous renal replacement therapy is more advantageous. 　　Key words：Continuous renal replacement；Intermittent hemodialysis；Acute renal failure