Ch2.3-随机化与药物编盲.pptxVIP

临床试验随机化与药物编盲上海交通大学基础医学院生物统计学教研室wangbingshun@本讲义参考了诸多教授见解：苏炳华、夏结来、姚晨、 … 随机化?Random allocation is one of the best ways that treatment comparisons made in the trial are valid.?Other methods such as blinding and placebos should be considered when appropriate.Deparment of Biostatistics, SJTU, School of Medicinewangbingshun@常见临床试验随机分配过程 被研究人群 随 机 分 配治疗方法A治疗方法B治愈未愈治愈未愈Deparment of Biostatistics, SJTU, School of Medicinewangbingshun@总 随机化?随机抽样 ?研究总体中每一单位等可能进入研究样本?随机化分组 ?受试者等可能地被分配到特定处理组?临床试验中随机化常常与盲法合用。?简单常用的随机化方法体Deparment of Biostatistics, SJTU, School of Medicinewangbingshun@ 随机化目的?使临床试验中的受试者有同等