牺牲硅胶法制备烟酸分子印迹聚合物及其性能研究-高校化学工程学报.PDF

第25 卷第5 期 高 校 化 学 工 程 学 报 No.5 Vol.25 2011 年10 月 Journal of Chemical Engineering of Chinese Universities Oct. 2011 文章编号：1003-9015(2011)05-0851-07 牺牲硅胶法制备烟酸分子印迹聚合物及其性能研究 谭 健, 晏荣军, 裘俊红 (浙江工业大学 绿色化学合成技术国家重点实验室, 浙江 杭州 310014) 摘 要：选用薄层层析硅胶作为牺牲载体，以烟酸为模板分子，丙烯酰胺为功能单体，乙二醇二甲基丙烯酸酯为交联 剂，合成了烟酸分子印迹聚合物(MIPs) 。通过考察功能单体种类及用量、交联剂用量及硅胶用量确定了制备MIPs 的最 佳工艺条件，制备得到的MIPs 吸附容量达到78.5 μmol⋅g− 1 。以烟酰胺作为竞争底物考察MIPs 的特异吸附性能，其分 离因子达到2.76 ，分离因子比为2.14 。重复耐用性实验表明，MIPs 具有很好的耐用性能。通过扫描电子显微镜(SEM) 对聚合物微观形貌进行表征，并以Scatchard 分析法对其结合性能进行了研究。结果表明，与用传统本体聚合法制备的 MIPs 相比，以牺牲硅胶法合成的MIPs 具有更好的特异吸附性能。 关键词：分子印迹聚合物；牺牲载体；烟酸；硅胶 中图分类号：O631.2 ； TB383 文献标识码：A Preparation and Performance Study of Nicotinic Acid-Imprinted Polymers with Silica Gel as Sacrificial Carrier TAN Jian, YAN Rong-jun, QIU Jun-hong (State Key Laboratory of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014, China) Abstract: Taking silica gel as sacrificial carrier and using acrylamide as the functional monomer, the ethylene glycol dimethacrylate as the cross-linker, the molecularly imprinted polymers (MIPs) with specific performances of recognition and adsorption towards to nicotinic acid were prepared in the presence of template molecule of nicotinic acid. The optimum preparation conditions were confirmed by investigating different kinds of monomer used, as well as the dosages of monomer, cross-linker and silica gel. The binding capacity of MIPs prepared under the optimum conditions reaches 78.5 μmol⋅g− 1. When the nicotinamide was selected as