中药成方制剂中风湿病相关方剂数据库的建立与处方分析.docVIP

中药成方制剂中风湿病相关方剂数据库的建立与处方分析 ? 微机应用? 中药成方制剂中风湿病相关方剂数据库的建立与处方分析 方勇飞,钟兵,王剑莉,唐明礼2王勇(1.第三军医大学西南医院中医?风湿科,重庆市400038; 2.重庆电脑报社,重庆市400013) 中图分类号R28文献标识码B文章编号1001—0408(2003)11—0667—04 摘要目的:利用计算机更好地为临床服务.方法:将《药品标准?中药成方制剂》第1册至第20册中近4000个中成药处方全 部录入计算机,用Access软件建立数据库,以全文检索方式筛选出涉及风湿和痹的处方共364个,建立中药成方制剂中风湿 病相关方剂子数据库,对单味药和不同给药途径成药的用药情况及所用药物的分类等进行统计分析.结果:364个风湿病相关处方 中共用药1043味,重复使用10次及以上的药物共106味,单味药使用频率排前10位的药物依次是当归,川芎,牛膝,川鸟,红花, 独活,防风,甘草,桂枝和羌活.对使用频率较高的50种药物进行归类分析,主要为活血祛瘀药,祛风湿药,辛温解表药,补益药及祛 寒药等.结论:祖国医学在治疗风湿病方面积累了丰富的临床经验,有大量的方剂与药物可供使用与研究,但也存在一些问题,如用 药过于繁杂,功效与主治描述用语模糊等,在今后的新药开发中应予高度重视. 关键词风湿病;中成药;方剂;数据库 EstablishmentandAnalysisofPrescriptionDatabaseofChinesePatentMedicinesAssociatedwithRheum- aticDiseases FANGYongfei,ZHONGBing,WANGJianli,WANGYong(Dept.ofTraditionalChineseMedicineand Rheumatology,SouthwestHospital,ThirdMilitaryMedicalUniversity,Chongqing400038) TANGMingli(NewspaperOfficeofPopularComputerWeek,Chongqing400013) ABSTRACTOBJECTIVE:ToutilizecomputertOgivebetterservicetOclinicalpractice.METHODS:About4000prescrip- tionsofChinesepatentmedicines,derivedfromphamaconcriteria:theChinesetraditionalpatentmedicinevolume1～20pub_ lishedbyMinistryHealthP.R.China,wereloggedintocomputerandcorrespondingdatabasewasestablishedbyusingMi— crosoftAccessdatabase.Bysearchingthekeywordsoffengshiorbiinthedatabase.364prescriptionswerecalculated out.Secondarydatabaseassociatedwithrheumaticdiseaseswasestablishedandanalysed.RESULTS:Itisfoundthatthereare 1043kindsofherbsinthe364prescriptionsassociatedwithrheumaticdiseases.106kindsofherbsarerepeatedmorethan10 times.Theherbsthatoccupytop10placesinfrequencyofuseareasfollows:ChineseAngelicaRoot;ChuanxiongRhizome; AchyranthesandCyathulaRoot;AconitumcarmichaeliDebx;Safflower;HeracleumHemsleyanumDiels;LedebouriellaRoot; Liquorice;CinnamonTwig;NotopterygiumRoot.Byclassifyingandanalyzingthefiftykindsofherbsusedinhighfrequency, theyaremostlyherbssuchaspromotingbloodcirculationandremovingbloodstasis,antirheumatics,diaphoreticspungentin flavourandwarminproperty.tonics,int