生物补片法阴道成形和腹膜代阴道成形治疗先天性无阴道临床疗效分析.docVIP

生物补片法阴道成形和腹膜代阴道成形治疗先天性无阴道临床疗效分析 　　【摘要】 目的：比较先天性无阴道患者采用生物补片阴道成形与经阴道盆腔腹膜代阴道成形的临床疗效。方法：选取2010年1月-2013年6月在本院行人工阴道成形术的MRKH患者35例，其中20例行生物补片法阴道成形术（生物补片组），15例行经阴道盆腔腹膜代阴道成形术（腹膜组）。比较两组患者的手术时间、术中出血量、术后肠功能恢复时间、住院时间、术后病率及手术费用。随访患者术后阴道长度、宽度，阴道黏膜化时间，术后并发症，患者及性伴侣的性生活满意度评分。结果：生物补片组患者的手术时间、出血量、术后肠功能恢复时间均显著优于腹膜组（P0.05）。两组患者的术后病率分别为25.0%（5/20）和26.7%（4/15），差异无统计学意义（P0.05）。两组患者的人工阴道长度、宽度比较差异均无统计学意义（P0.05），但生物补片组患者及性伴侣对性生活的满意度评分高于腹膜组，差异有统计学意义（P0.05）。结论：生物补片法阴道成形术与经阴道盆腔腹膜代阴道成形术均为有效的人工阴道成形术，生物补片法阴道成形术的方法更简便、手术损伤更小、恢复更快，患者术后对性生活的满意度更高，但费用较昂贵。 　　【关键词】 人工阴道成形术； 生物补片代阴道； 经阴道盆底腹膜代阴道； 性生活满意度 　　【Abstract】 Objective：To compare the clinical effect of artificial vaginoplasty with biological patch and vagina construction by pelvic peritoneum in the treatment of congenital absence of vagina.Method：35 patients with MRKH who were treated with artificial vaginoplasty in our hospital from January 2010 to June 2013 were selected as the research objects，20 patients were treated with artificial vaginoplasty with biological patches（biological patch group），15 patients were treated with artificial vaginoplasty by pelvic peritoneum（peritoneum group）.Then the operative time，blood loss，postoperative intestinal function recovery time，hospital stay，postoperative morbidity and surgical costs of two groups were compared，and the postoperative vaginal length，width，time of vaginal mucosa，complication，patients and sexual partners sexual satisfaction scores were followed up.Result：The operative time， blood loss， postoperative intestinal function recovery time of biological patch group were all significantly lower than those of peritoneum group（P0.05）.The postoperative morbidity of the two groups were respectively 25.0%（5/20） and 26.7%（4/15），there was no significant difference（P0.05）.The vaginal length and width of two groups had no significant differences（P0.05），while the sexual satisfaction scores of biological patch group were all higher than those of peritoneal group，the differences were all significant（P 　　【Key wor