子宫内膜异位症临床诊治的探讨.docVIP

子宫内膜异位症临床诊治的探讨 　　[摘要] 目的：对子宫内膜异位症的临床诊治进行探讨。方法：以2009年1～6月来本院进行治疗的46例子宫内膜异位症患者作为分析和研究对象，根据患者所接受药物治疗的不同，将患者分为治疗组和对照组，对照组患者通过服用短效口服避孕药、经脉滴注孕激素、促性腺激素等传统药物治疗方式进行治疗，治疗组患者均通过口服米非司酮片的方法对子宫内膜异位症进行治疗。结果：无论是在治疗的总有效率还是在复发率方面，治疗组患者都要优于对照组患者，且P＜0.05，差异具有统计学意义。结论：米非司酮不仅治疗效果较为明显，并且无不良反应，患者的耐受性和复发率均较为满意，为子宫内膜异位症患者的临床治疗提供了一种新的选择，可以在临床中进行进一步的推广和应用。 　　[关键词] 子宫内膜异位症；临床诊治；妇产科；促性腺激素 　　[中图分类号] R711.71 [文献标识码]C [文章编号]1674-4721（2011）04（c）-171-02 　　 　　Clinical diagnosis and treatment of endometriosis 　　YANG Kangmei 　　The People′s Hospital of Wuchuan City, Guangdong Province, Wuchuan 524500, China 　　[Abstract] Objective: Endometriosis on the diagnosis and treatment were discussed. Methods: January 2009 to June 2009, for treatment of 46 patients with endometriosis examples for analysis and study in our hospital, patients receiving drug treatment according to different patients were divided into treatment group and control group the control group patients by taking short-acting oral contraceptives, progesterone infusion meridians, gonadotropin therapy and other traditional way of treatment, all patients treated with oral mifepristone tablets by the method of the endometriosis treatment. Results: Both the total effective in the treatment of relapse rate or in the treatment group than the control group of patients had disease, and P0.05, statistically significant difference. Conclusion: The therapeutic effect of mifepristone is not only more obvious, and no adverse reactions, tolerance and patients are more satisfied with the recurrence rate for patients with endometriosis, a new clinical treatment of choice, can clinic for further promotion and application. 　　[Key words] Endometriosis; Clinical diagnosis and treatment; Obstetrics and Gynecology; Gonadotropin 　　 　　子宫内膜异位症简称EMS，是一种具有雌性激素依赖性的良性疾病，但是，该病也具有血管形成、黏附和组织侵袭功能等生物学行为，其发病和发展与患者异位内膜对凋亡的抵抗力增强、内分泌功能紊乱、免疫功能异常、盆腹腔内环境改变等有着直接的联系。本院自2009年开始利用米非司酮进行子宫内膜异位症的临床治疗，取得了良好的治疗效果。米非司酮简称RU486，其作用部位为患者的肾上腺皮质、性腺和子宫内膜，但是随着该药应用范围的逐渐扩大，对其研究也开始向子宫内膜异位症方向集