关于国外“渗性脱髓鞘综合征”文献之复习：反思.docVIP

河南大学学报（医学版）2012，第31卷，第1期，第55~64页 PAGE PAGE 1 关于国外“渗透性脱髓鞘综合征”部分文献之复习:初步反思 ——肝移植术后/严重呕吐导致的疑似VB1缺乏系列症、低钾性肌麻痹与碱中毒性脑病 张海鹏，曾伏虎，杜长生，翟所鑫，陈宗羡，李玉清，刘庆梅，朱玉忠，王荣明，张 力 [关键词] 脑桥中央髓鞘溶解症；脑桥外髓鞘溶解症；渗透性脱髓鞘综合征；Wernicke脑病；低钾性肌麻痹，乏力，非，周期性；肝移植术；环孢素，FK506；肝硬化；胎肝移植；脾脏部分切除，脾-腔/肾静脉分流术；癫痫；脑桥下部旁正中（血管）综合征，双侧型；低钠性脑病；碱中毒性脑病；脚气性心脏病，维生素B1缺乏症 Something Related to Beriberi, Hypokalemic Non-periodic Paralysis or the Encephalopathy of Alkalosis: A Primary Reretro-consideration on Some International Documentations Concerning the “Osmotic Demyelination Syndrome”Seeming to Include Central Pontine Myelinolysis Zhang Hai-peng1,Zeng Fu-hu2,Du Chang-sheng3, Zhai Suo-xin2, Chen Zong-xian2,Li Yu-qing1,Liu Qing-mei1，Zhu Yu-zhong1,Wang Rong-ming1 and Zhang Li4. 1.ICU, Department of Neurosurgery,Neurology or General Surgery,The ZHUO-LU County Hospital,Zhangjiakou Academy of Medicine Sciences,Hebei North University,Zhuolu,Zhangjiakou075000,Hebei,P.R.China;2.Department of Neurology or Neurosurgery,The 2nd Hospital Affilited to Zhangjiakou Academy of Medicine Sciences,Hebei North University,Zhangjiakou075000,Hebei;3. Department of Neurology, General Hospital of The People’s Armed Police Forces of China(GHPAPFC) ,Beijing100039, P.R.China;4.Basic Medical Center, Zhangjiakou Academy of Medicine Sciences,Hebei North University,Zhangjiakou075000,Hebei, P.R.China. （E-mail: heapprenzcomhard@163.com ） [Abstract] Objectives: To explore the main etiological factors of central pontine myelinolysis (CPM) and of the “osmotic demyelination syndrome(ODS)”that occurs after hepatic transplantation, to explore the differential diagnosing the manifestation consisting of dysarthria, dysphagia and quadriplegia presented after vomiting for a number of times ,and to explore which fraction to be mainly involved by the “ODS” ,what to be the pathological mechanism of the “ODS” ,and how to prevent the “ODS”.Methods:Physiopathological principles are applied on the base of the clinical certificates ,the diagnostic results differring f