原发性醛固酮增多症患者钙磷代谢情况及其与成纤维生长因子23相关.PDF

宀崡鐜颁唬涓村簥澶栫2018骞?鏈堢18鍗风2鏈烲ingnanModernClinicsinSurgery锛孉pr.2018锛孷ol.18No.2 137 鍘熷彂鎬ч啗鍥洪叜澧炲鐥囨偅鑰呴挋纾蜂唬璋㈡儏鍐靛強 鍏朵笌鎴愮氦缁寸敓闀垮洜瀛?3鐩稿叧鎬у垎鏋 # * 鏋楄幑锛屽攼鑿婅嫳 锛屽紶灏戠幉 锛岄粠閿嬶紝寮犲皬浜戯紝楹︽ⅷ鑺筹紝閮锛屼弗鍔 锛绘憳瑕侊冀 鐩殑 姣旇緝鍘熷彂鎬ч啗鍥洪叜澧炲鐥囷紙PA锛夊拰鍘熷彂鎬ч珮琛€鍘嬶紙EH锛夋偅鑰呴挋纾蜂唬璋㈠拰鎴愮氦缁寸敓 闀垮洜瀛?3锛團GF23锛夋按骞崇殑宸紓锛屾帰璁ㄤ簩鑰呯殑鐩稿叧鎬с€傛柟娉 閫夋嫨鍥犫€滈珮琛€鍘嬫煡鍥犫€濅綇闄㈢‘璇婄殑璧 鏂欏畬鏁寸殑鐥呬緥锛屾寜鎬у埆銆佸勾榫勩€侀珮琛€鍘嬫按骞冲強鍏剁梾绋嬬瓑鍖归厤鍘熷垯绾冲叆123渚婸A鎮ｈ€呭拰123渚婨H 鎮ｈ€咃紝姣旇緝涓ょ粍鎮ｈ€呯殑閽欑７浠ｈ阿鎸囨爣鐨勫樊寮傚苟鍒嗘瀽鍏朵笌FGF23鐨勫叧绯汇€傜粨鏋 锛?锛塒A缁勭殑FGF23銆 PTH姘村钩楂樹簬EH缁勶紝鍒嗗埆鏄?71.31 pg/mL锛?73.91锛?04.34锛塿s 160.41 pg/mL锛?18.08锛?35.60锛夊拰 74.5pg/mL锛?6.5锛?1.0锛塿s.43.60pg/mL锛?3.75锛?0.25锛夛紝鍏跺樊寮傚叿鏈夌粺璁″鎰忎箟锛圥0.001锛夛紝浣嗚閽欍€佽纾 姘村钩浣庝簬EH缁勶紙2.18卤0.17mmol/Lvs.2.33卤0.17mmol/L鍜?.013卤0.204mmol/Lvs. 1.127卤0.190mmol/L锛 P0.001锛夈€傦紙2锛塒A缁勪腑FGF23涓庝笌琛€纾锋按骞冲憟璐熺浉鍏筹紙r=-0.502锛孭=0.001锛夛紝涓嶱TH姘村钩鍛堟鐩稿叧 锛坮=0.349锛孭=0.030锛夈€傦紙3锛塒A缁勪腑闅忕潃閱涘浐閰按骞崇殑閫掑锛孎GF23鍛堜笂鍗囪秼鍔匡紙P0.05锛夈€傜粨璁 PA鎮 鑰匜GF23姘村钩鏄捐憲涓婂崌锛孎GF23姘村钩涓庤纾峰拰PTH姘村钩鐩稿叧锛屼笖FGF23涓庨珮閱涘浐閰按骞崇浉鍏炽€ 锛诲叧閿瘝锛 鍘熷彂鎬ч啗鍥洪叜澧炲鐥囷紱鎴愮氦缁寸敓闀垮洜瀛?3锛涢挋纾蜂唬璋 doi锛?0.3969/j.issn.1009鈦?76X.2018.02.004 涓浘鍒嗙被鍙凤細R692 鏂囩尞鏍囪瘑鐮侊細A Calciumandphosphorusmetabolisminpatientswithprimaryaldosteronismanditscorrelation withfibroblastgrowthfactor23 # LINYing锛孴ANGJuying 锛孼HANGShaoling锛孡IFeng锛孼HANGXiaoyun锛孧AILifang锛孏UOYing锛孻ANLi Department of Endocrinology锛孲un Yat鈦僺en Memorial Hospital锛孲un Yat鈦僺en University锛孏uangzhou 510120锛孋hina #Contributedequally Correspondingauthor锛歓HANGShaolin锛孍鈦僲ail锛歾hangshaoling88@ 锛籄bstract锛 Objective Tocomparecalciumandphosphorusmetabolismandfibroblastgrowthfactor 23 锛團GF23锛塴evelinpatientswithprimaryaldosteronism 锛圥A锛塧ndessentialhypertension 锛圗H锛夛紝andto explorethecorrelationbetweenthem. Methods Atotalof 123caseswithPAand 123caseswithEH individuallymatched1锛? bygender锛宎ge锛宐loodpressureanddurationofhypertensionwererecruited from in鈦僪ospital patients who were hospitalized because of suspicion of secondary hypertension. The differencesincalciumandphosphorusmetabolismaswe