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ACOG COMMITTEE OPINION
Number 742
Committee on Obstetric Practice
The Academy of Breastfeeding Medicine; the American College of Nurse-Midwives; the Association of Women’s Health, Obstetric and Neonatal Nurses;
the Society for Maternal–Fetal Medicine; the Society for Obstetric Anesthesia and Perinatology; and the Society of Obstetricians and Gynaecologists of
Canada endorse this document. This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on
Obstetric Practice, in collaboration with the American College of Nurse-Midwives liaison member Tekoa L. King, CNM, MPH; American Academy of
Family Physicians liaison member Beth Choby, MD; and committee member Yasser Y. El-Sayed, MD.
Postpartum Pain Management
ABSTRACT: Pain and fatigue are the most common problems reported by women in the early postpartum
period. Pain can interfere with a woman’s ability to care for herself and her infant. Untreated pain is associated with
a risk of greater opioid use, postpartum depression, and development of persistent pain. Nonpharmacologic and
pharmacologic therapies are important components of postpartum pain management. Because 81% of women in
the United States initiate breastfeeding during the postpartum period, it is important to consider the drug effects of
all prescribed medications on the mother–infant dyad. Multimodal analgesia uses drugs that have different
mechanisms of action, which potentiates the analgesic effect. If opioids are included, a multimodal regimen used
in a stepwise approach allows for administration of lower doses of opioids. Given interindividual variation in
metabolism of opioids, as well as the risk of maternal and neonatal adverse effects in women who are ultra-rapid
metabolizers of codeine, monitoring for excessive sedation and other adverse effects in infants is prudent for
women who are prescribed opiates. Although the U.S. F
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