补肾活血汤干预老年高血压肾虚血瘀证临床的研究.docVIP

补肾活血汤干预老年高血压肾虚血瘀证临床的研究 　　摘要：目的 观察补肾活血汤干预老年高血压肾虚血瘀证患者的临床疗效。方法 采用随机数字表法将106例纳入患者分为对照组和治疗组各53例，对照组采用西医常规治疗，治疗组在此基础上加服补肾活血汤，疗程8周。观察2组治疗前后中医证候、血压及血清三酰甘油（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、超敏C反应蛋白（hs-CRP）、肿瘤坏死因子（TNF-α）、白细胞介素-6（IL-6）的变化。结果 治疗组降压疗效总有效率为94.33%（50/53），对照组为77.35%（41/53）;治疗组中医证候疗效总有效率为96.22%（51/53），对照组为79.24%（42/53）;治疗后治疗组TG、TC、LDL-C、HDL-C、hs-CRP、TNF-α、IL-6均明显改善，与对照组比较差异有统计学意义（Plt;0.05）。结论 补肾活血汤联合西医常规疗法治疗老年高血压病肾虚血瘀证有较好的疗效。 　　关键词：补肾活血汤;老年高血压;肾虚血瘀证;中西医结合疗法 　　DOI：10.3969/j.issn.1005-5304.2015.02.008 　　中图分类号：R259.441文献标识码：A 文章编号：1005-5304（2015）02-0025-03 　　Clinical Research on Elderly Hypertension of Kidney Deficiency and Blood Stasis Syndrome Intervened with Bushen Huoxue Decoction TIAN Yuan1， LI Jie2（1.Shandong University of Traditional Chinese Medicine， Jinan 250355， China;2.Qingdao Hiser Medical Group， Qingdao 266033， China） 　　Abstract：Objective To observe the clinical efficacy of Bushen Huoxue Decoction on elderly hypertension of kidney deficiency and blood stasis syndrome. MethodsTotally 106 patients with elderly hypertension of kidney deficiency and blood stasis syndrome were divided into control group （53 cases） and treatment group （53 cases）， according to random number table method. The control group was treated with routine western medicine， while the treatment group was given Bushen Huoxue Decoction along with western medicine treatment for 8 weeks. The changes of TCM syndrome， blood pressure， TG， TC， LDL-C， HDL-C， high sensitivity C reactive protein （hs-CRP）， interleukin-6 （IL-6）， and tumor necrosis factor-α（TNF-α） before and after treatment of the two groups were observed. Results The total effective rate of anti-hypertension was 94.33% （50/53） in the treatment group and was 77.35% （41/53） in the control group. The total effective rate of clinical symptoms was 96.22% （51/53） in the treatment group and was 79.24% （42/53） in the control group. After treatment， TG， TC， LDL-C， HDL-C， hs-CRP， IL-6， and TNF-α were improved signific