中老年男性睾酮部说分缺乏症.ppt

* * 前面讲到，睾酮是由睾丸间质细胞分泌的。在中老年男性，随着年龄的增加，间质细胞数量是逐步减少的。 Reference Neaves WB, Johnson L, Porter JC, Parker CR, Petty CS. Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men. J Clin Endocrinol Metab 1984;55:756-763 * * Historically,it has been always recognized that androgens play in maintaining sexual activity was thought to be via it role mainly on sexual interest. But with accumulating evidence both animals and humans to androgen’s local effects: Animal studies showed that expression of nitric oxide synthase (NOS) gene inside the penis depends on the presence