分子生物学杨洋rna剪接.pptx

Ch 12: Mechanisms of transcription Ch 13: RNA splicing Ch 14: Translation Ch 15: The genetic code;CHAPTER 6 RNA Splicing （第六章 RNA剪接）;Figure 13-1;Most of the eukaryotic genes are mosaic (嵌合体), consisting of intervening sequences separating the coding sequence（割裂基因） Exons (外显子): the coding sequences Introns (内含子) : the intervening sequences RNA splicing: the process by which introns are removed from the pre-mRNA（从前mRNA中除去内含子的过程） 这个过程将前mRNA转化为成熟RNA，必须绝对精确，避免在外显子连接处缺少或增多哪怕一个核苷酸 Alternative splicing (可变剪接): some pre-mRNAs can be spliced in more than one way , generating alternative mRNAs. 60% of