补骨脂酚体外代谢研究进展.docxVIP

 PAGE \* MERGEFORMAT 1 Page21 Page0 题 目： 补骨脂酚的体外代谢研究进展 目 录 TOC \o 1-3 \h \u  HYPERLINK \l _Toc31697 摘要  PAGEREF _Toc31697 4  HYPERLINK \l _Toc6140 关键词  PAGEREF _Toc6140 4  HYPERLINK \l _Toc7729 前言  PAGEREF _Toc7729 4  HYPERLINK \l _Toc32735 1.补骨脂酚的来源  PAGEREF _Toc32735 5  HYPERLINK \l _Toc12447 2.补骨脂酚的药理活性  PAGEREF _Toc12447 5  HYPERLINK \l _Toc17653 3.补骨脂酚的体内代谢研究进展  PAGEREF _Toc17653 5  HYPERLINK \l _Toc23652 3.1补骨脂酚毒性  PAGEREF _Toc23652 5  HYPERLINK \l _Toc47 3.2药代动力学  PAGEREF _Toc47 5  HYPERLINK \l _Toc24633 3.3代谢途径研究  PAGEREF _Toc24633 6  HYPERLINK \l _Toc201 4.补骨脂酚的体外代谢研究进展  PAGEREF _Toc201 8  HYPERLINK \l _Toc5311 综述  PAGEREF _Toc5311 13  HYPERLINK \l _Toc4920 3.结语  PAGEREF _Toc4920 17  HYPERLINK \l _Toc17916 4. 展望  PAGEREF _Toc17916 17  HYPERLINK \l _Toc14673 5. 致谢  PAGEREF _Toc14673 18  补骨脂酚的体内代谢研究进展 摘要：中药补骨脂为豆科植物补骨脂 Psoralea corylifo-lia L.的干燥成熟果实。补骨脂酚是补骨脂的主要成分之一，是一种单萜类化合物,补骨脂酚具有肖炎退热、抗菌、抗病毒、抗癌、保肝和雌激素样作用等药理活性。通过对近年来国内外对补骨脂酚体内外代谢研究进行综述，有利于对该类成分体内药效的物质基础和作用机制进行深入探索，可以更加深入研究补骨脂酚的药理作用，为新药研发提供理论依据。 关键词：补骨脂酚；代谢；进展 Ｒesearch Progress on Metabolism of Bakuchiol in vivo and in vitro Abstract: Chinese medicine Psoralen is the dried ripe fruit of leguminous plants Psoralea corylifo-lia L. Bakuchiol is one of the main components of Psoralen, is a monoterpenoid compounds, Bakuchiol has anti-inflammatory and antipyretic, anti-bacterical, anti-virus, anti-cancer, liver and estrogen-like pharmacological acticity. This paper summarizes the progress of metabolism of Bakuchiol in vitro and in vivo from domestic and abroad in recent years, which is helpful to further explore the material basis and mechanism of the effect of these components, in order to further study the pharmacological effects of Bakuchiol’s chemical substances based on the development of new drugs to provide a theoretical basis. Key words: Bakuchiol; Metabolism; Progress123  INCLUDEPICTURE H:\\肖申克的救赎\\