局部麻才醉（英文）.pptVIP

Regional Anesthesia 一、Nerve Blocks LOCAL ANESTHETICS(LA) 十八世纪中，人们咀嚼古柯叶感受舒适感和增加耐力 1860年，从古柯叶中发现了可卡因 1884年，可卡因先后用于眼部局麻手术、颌神经阻滞、脊髓麻醉、硬膜外麻醉和蛛网膜下腔阻滞麻醉 Local anesthetics of Peripheral nerve block Drug dose concentration duration Ropivacaine 150~200mg 0.2~0.5% 6~12h Bupivacaine 150mg 0.2~0.5% 6~12h Lidocaine 400mg 0.5~1% 1~3h ◆The toxicity of Local anesthetics Reason Central Nervous System Toxicity Cardiovascular System Toxicity Prevention Excessive doses of LA Systemic absorption of LA intravascular injection of LA Tes