大内科学全套课件.pptVIP

Treatment phases Induction therapy: the aim is to bring about remission , that is leukemic cells are no longer found in the bone marrow and the recovery of normal hematopoiesis Post-remission therapy: to eliminate any leukemia cells potential hiding in the body Special subtypes Acute promyelocytic Leukemia (APL): because of the small particles (procoagulants) inside the APL cell, DIC are commonly seen in this type of AML Normal APL Genes essential for differentiation are shut down by the fusion proteins PML-RARalpha Differentiation agents (all-trans retinoic ac