抗生素发酵生在产工艺学.pptVIP

概述 生产前期研究 生产菌改良 生产工艺过程 发酵条件的控制 提取和精制 Introduction Research in Lab Strain improvement Production processing Fermentation control Isolation purification 抗生素 是生物在其生产活动过程中所产生，并能在低微浓度下有选择性地抑制或杀灭其他微生物或肿瘤细胞的有机物。 Antibiotics Any organic substances produced by various organisms that have the power of arresting the growth of other microorganisms or of destroying them. 历史 1929年，英国弗莱明发现青霉素 二战期间，大规模发酵生产 世界上最早用于临床的抗菌素 History Penicillin was discovered by Fleming in 1929. World War II, fermented in large-scale The first major antibiotic to be commercialized 根据抗生素的作用机制分类 (Modes of Action of Antib