天然产物活性成分提取分离研究进展.PDFVIP

第35 卷 第3 期 经济林研究 Vol. 35 No.3 2017 年9 月 Nonwood Forest Research Sep. 2017 Doi:10.14067/ki.1003-8981.2017.03.039 http: // 天然产物活性成分提取分离研究进展 a，b a，b a，b c 章怀云 ，刘 俊 ，毛绍名 ，孙汉洲 （中南林业科技大学 a. 林业生物技术湖南省重点实验室；b. 生命科学与技术学院；c. 理学院，湖南 长沙 410004 ） 摘 要：从动物、植物、微生物体内分离得到的某些天然成分，具有结构的多样性和生物活性的多样性，在新药 和药物先导化合物的开发中起着重要作用。传统分离技术分离效率低而成本高，新技术的出现将有效改善这一 不利局面。为给天然产物活性成分的开发应用提供参考依据，综述了近年来国内外天然产物活性成分提取分离 技术的研究进展，并对天然产物活性成分提取分离中存在的问题进行了探讨，还对天然产物活性成分的利用前 景进行了展望。 关键词：天然产物；活性成分；提取；分离；综述 中图分类号：S609.9；TQ028.8 文献标志码：A 文章编号：1003—8981(2017)03—0244—07 Advances in researches on extraction and separation of active constituents from natural products ZHANG Huaiyuna,b, LIU Juna,b, MAO Shaominga,b, SUN Hanzhouc (a. Hunan Province Key Laboratory of Forestry Biotechnology; b. College of Life Sciences and Technology; c. College of Science, Central South University of Forestry Technology, Changsha 410004, Hunan, China) Abstract: Some natural ingredients, extracted from animals, plants and microorganisms, have diversity in structure and bio-activity, and play an important role in developing new medicine and medicine lead compounds. Newly-emerging separation technologies will change the unfavorable situation where traditional ones are of low efficiency and high cost. In order to provide some references for development and application of active constituents from natural products, the research progress of extraction and separation technologies of active constituents from natural products at home and abroad were reviewed, the existing issues in extraction and sepa