基于reads引导的基因组序列拼接-计算机科学与技术专业论文.docxVIP

Abstract Genome assembly is the core issue of bioinformatics, and assembling reads produced by DNA sequencing can generate genome sequences. The emergence of next generation sequencing has provided great aid for the life science research on major issues, but at the same time, it brings genome assembly an unprecedented challenge due to its data of mass, short length and relatively low precision, while traditional algorithms are no longer applicable. Development of sequence assembly software that could meet practical application has become the most important research topic. Firstly, this paper