病椎置短椎弓根钉治疗多节段胸腰椎结核的临床分析.pdfVIP

青海大学硕士学位论文 Abstract Abstract Objective: To observe clinical effects of affected vertebrae short pedicle screw placement, focus clearance and bone graft fusion internal fixation for the treatment of multi-level thoracolumbar tuberculosis, and to seek improvement and therapeutic efficacy of the surgery for multi-level thoracolumbar tuberculosis. Method: 40 patients with multi-level thoracolumbar tuberculosis (and with spinal tuberculosis diagnosis after surgeries) who were treated in the Affiliated Hospital of Qinghai University from February 2012 to February 2014 are enrolled. For the patients, 15 cases are female and 25 are male; the age range is 26 to 63 years with an average of 43.4±2.3 years; the disease courses are from 6months to 2 years with an average of 12 months. 14 patients are with a focus on thoracic vertebra, 5 are with tuberculosis of lumbar spinal, while 21 were diagnosis with tuberculosis of both. All patients were diagnosed with CT, X rays and MRI to meet the diagnosis criteria of multilevel thoracolumbar tuberculosis. All patients complain sever pain, limited activities, spinal kyphosis deformity, neural dysfunction and others. For Frankel classification, 6 patients were divided into A Grade, 10 were B Grade, as well as 12 and 12 patients were C Grade and D Grade respectively. Neural functional improvement of before and after surgeries is evaluated according to Frankel classification standards. For pre-operation, the average of Cobb angle and the average of anterior affected vertebral height (%) that were measure from imaging results were 35.6±3.7 and 40.5%±6.3. Conventional antituberculous chemo