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结论 应用不同修复材料治疗牙槽突裂,通过影像学和组织学检测,观察上
颌骨发育情况及局部成骨能力,相互对比,证实各种材料植入牙槽突裂隙内,(1)
对上颌骨发育有不同程度的影响:其中自体髂骨影响最小,脱钙骨次之,骨水泥
影响最大;(2 )从成骨能力上看,从好到差依次为:髂骨组,脱钙骨组,骨水泥
组,髂骨组明显优于其他各组。
关键词 自体髂骨 脱钙骨 骨水泥 CT 三维重建 牙槽突裂
2
The experimental study on bone reconstruction of alveolar
cleft by different materials
Abstract
Object: Establish rabbit’s model of unilateral alveolar cleft , discuss the effect of
maxillary growth further and development and compare the respective osteogenic
capability to regenerate alveolar cleft which used autogenous iliac bone ,pure
decalcified bone material and acrylic cement.
Method: (1) choose 40 New Zealand white rabbits (8 weeks old, 1~1.2kg.) as
samples and result in their unilateral alveolar cleft through operation; (2) these 40
rabbits were averagely divided into 4 groups randomly: iliac bone group, decalcified
bone group, acrylic cement group and blank group 2 weeks after operation. The other
three groups are implanted autogenous iliac bone, ,pure decalcified bone material and
acrylic cement into the defects respectively except that the blank group was
subjected to no disposal; (3) observe their skulls by three-dimensional CT after 2
weeks ,4 weeks,6 weeks and 8 weeks respectively and measure the distance between
sutures of maxillary, moreover, obtain the CT numbers to master the development of
maxillary.2 rabbits in each group were sacrificed to obtain their tissue samples and
observe them to master the information of osteogenic capability. We conduct paired
t-test analysis on the data of the healthy sides and sick sides by applying SPSS 19.0
software and conduct one-way analysis of variance(LSD) to the data of different
groups. In ad
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