圣琪多元发三酵培养基-酵母培养基篇.ppt

* 23 It’s in two parts, Below the Line/Above the Line Describe Below and Above (start with Below) (Above…start with See It) It’s not wrong to go below the line, in fact, it’s a very natural place to go when faced with difficulties However, it’s ineffective to get stuck there (don’t set up camp) How many feel that getting more employees above the line will significantly improve results? Jack in the Box (1993); hamburger meat contaminated E. coli. 4 deaths, 600 sick. Blamed supplier, filed lawsuit. Supplier blamed Jack in the Box (didn’t cook correctly). They did destroy meat, raised cooking temps, paid medical bills. However, there denial gave customers the impression, not concerned with safety. Revenues did not recover for 7 years. Tylenol (1982); 37% of market for painkillers. Tylenol laced with cyanide, resulted in 7 deaths in Chicago area. Immediately asked, “how do we protect people?” Immediately alerted consumers nation-wide, do not take Tylenol. Recalled 31 million bottles (100 million dollars). No blame game, investigated to make sure never to happen again. Developed safety seals. Within 3 months, recovered market share. How many of you feel safe in using Tylenol today? * 圣琪生物多元发酵培养基 酵母培养基篇 圣琪生物酵母培养基 圣琪生物结合不同发酵客户的不同的菌种特性、不同的培养基营养需求、不同的产品的发酵代谢途径、不同产物的合成机制等多个因素生产适合不同发酵产品的不同需求的培养基。 圣琪生物的酵母培养基 开发背景 1、与国外酵母培养基产品相比，国内的一些培养基在某些发酵产品的应用效果上与国外还有一点差距，需要针对这些产品生产的营养需求特征来开发特定的培养基，提高产品的竞争力。 2、生物产业的竞争在加剧，高附加值和采用清洁生产工艺生产的新型发酵产品越来越多，传统的酵母培养基已不能完全满足行业的发展需求。大部分发酵产品是微生物的初级代谢产物或次级代谢产物，特别是微生物的次级代谢过程复杂，其中培养基的调节作用非常关键，有机氮源中的多营养成分对次级代谢的促进作用和反馈抑制作用往往同时存在，所以培养基生产厂家需要加强对发酵代谢调控理论的研究，通过发酵代谢调控理论来分析产物的生成原理，将培养基的生产和产品生产紧密的结合起来，使培养基中的各营养成分与发酵产品的生产工艺需求及产物表达原理更匹配。 应用领域 目前，酵母培养基已经被广泛应用于抗生素、生物催化、生物防腐剂、生物有机酸、维生素、生物多糖、酶制剂、核酸、氨基酸、基因工程药、微生态、脂肪酸及藻类等微生物发酵产品的生产中。蛋白质、氨基酸、核酸、维生素、微量金属元素等营养物质含量均衡合理的酵母培养基能显著提升发酵产品得率。在一些采用营养缺陷型生产菌种或基因工程菌种类产品的生产中，加入酵母培养基后，产品生产更稳定，可显著的提高产品产量，缩短发酵时间。 产品型号 应用领域 L601/P601 微生态（厌氧发酵）、普鲁兰糖、谷胱甘肽、乳酸链球菌素、透明质酸、鼠李糖脂、部分放线菌种子培养