表面活性剂超声提取莲子心总生物碱工艺研究.pdfVIP

Hans Journal of Medicinal Chemistry 药物化学, 2014, 2, 21-29 Published Online August 2014 in Hans. /journal/hjmce /10.12677/hjmce.2014.23004 Surfactant—Mediated Ultrasonic-Assisted Extraction of Total Alkaloids of Plumula Nelumbinis Ping Luo, Junjie Sun, Shasha Wang, Jun Zhang School of Chemistry and Chemical Engineering, CQU, Chongqing Email: cstpw@163.com, cqujunjie@163.com th th th Received: Jun. 29 , 2014; revised: Jul. 4 , 2014; accepted: Jul. 11 , 2014 Copyright © 2014 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Abstract Ultrasonic assisted ethanol extraction of alkaloids from Plumula Nelumbinis was studied. The ef- fects of ultrasonic power, ultrasonic time, immersion time, ethanol volume fraction and solid-liq- uid ratio on the extraction rate of alkaloids were investigated by single factor experiment, and the extraction parameters were optimized by orthogonal test. Under the best conditions, the influence of surfactants of Tween20, Tween60, Tween80, Span80, APG0810 and APG1214 on the extraction rate of alkaloids were illustrated. The results showed that under the best conditions of ultrasonic power 105 W, ultrasonic time 40 min, immersion time 30 min, ethanol volume fraction 70% and solid-liquid ratio 1:30, the extraction rate of alkaloids was 138.231 mg/g. By adding APG0810 0.02 g/mL, the extraction rate of alkaloids could be improved by 13.8% to 157.268 mg/g, which indi- cated that surfactant could improve the effect of ultrasonic extraction of alkaloids from Plumula Nelumbinis markedly. Keywords Alkaloids, Plumula Nelumbinis, Surfactant, Ultrasonic Extraction 表面活性剂——超声提取莲子心总生物碱 工艺研究