青春期多囊卵巢综合精征诊治共识.pptVIP

Diagnostic features of PCOS are hirsutism, anovulation, and polycystic ovaries, which show arrested follicular maturation; obesity and insulin resistance are frequently associated conditions. The major biochemical feature of PCOS is androgen excess, which causes hirsutism. Androgens also appear to inhibit the negative-feedback effects of estrogens and progesterone on pulsatile LH release. Women with PCOS have increased pulsatile GnRH release, which results in higher levels of LH and lower levels of FSH in most individuals. Higher LH (and insulin) levels seem to cause increased androgen product