超选微导管介入治疗肝癌的临床研究.pdfVIP

815 实用医技杂志2010 年9 月第17 卷第9 期 Journal of Practical Medical Techniques ，September 2010 ，Vol. 17 ，No. 9 · · 超选微导管介入治疗肝癌的临床研究 上海市浦东新区公利医院（200135） 徐志峰 陈石伟 乔德林 【摘 要】 目的 研究超选微导管系统在原发性肝癌化疗栓塞中的应用价值。方法 将肝癌介入栓塞治疗的患 者分为普通栓塞组和微导管栓塞组，普通组55 例，微导管组85 例。普通栓塞组常规采用5F RH 导管或5F Cobra 导 管行超选择栓塞治疗，微导管栓塞组采用SP 3F 同轴微导管作超选肝段或者亚肝段的肿瘤供血血管栓塞治疗，并观 察疗效和不良反应。结果 治疗3 周后，超微导管组的治愈率为77% （65/85），较普通导管组51% （28/55）明显提高， 碘油沉积量方面，超微导管组较普通导管组明显提高（P0.05），2 组治疗后甲胎蛋白较术前明显降低，以超微导管组 更为明显（P0.05），而不良反应方面，超微导管组的肝功能损害较普通导管组轻，差异有统计学意义（P0.05）。结论 微导管的使用可提高栓塞的疗效，避免并发症，肝功能损害轻微，具有较好的临床应用价值。 【关键词】 微导管系统；肝肿瘤；放射学，介入性；化疗栓塞，治疗性 Clinical study of micro catheter system on interventional therapy of primary hepatic carcinoma XU Zhi-feng, CHEN Shi-wei, QIAO De-lin. Pudong New Area Public Hospital of Shanghai ，Shanghai 201400 ，China 【Abstract 】 Objective To study the value of micro catheter system in chemoebolization of primary hepatic car- cinoma （PHC）. Methods All patients were divided of into two groups ，conventional group （group A）and micro catheter embolization therapy group （group B）. There were 55 cases in group A, and 85 cases in group B. RH catheter or Corbra catheter were used in group A. Superselective liver segmental or liver subsegmental tumor feeding artory to embolize with SP 3F coaxial microcatheter were used in Group B. The therapeutic effect and side effect were observed. Results After 3 weeks ′ treatment, the cure rate （77%）in group B obviously increased than that （51%）in group A （P0.05）. In sediment yield of iodized oil deposit, there was increased in group B than group A （P 0.05）. In side effect, the liver function was damaged lighter in group B than group A, there was obvious difference between two groups （P0.0