噪声性耳聋易感基因研究进展.pdfVIP

Asian Case Reports in Otolaryngology 亚洲耳鼻咽喉科病例研究, 2014, 2, 5-9 Published Online June 2014 in Hans. /journal/acro /10.12677/acro.2014.22002 Progress in Research on Susceptibility Genes Associated with Noise-Induced Hearing Loss 1 2* Xinyan Chen , Fuquan Chen 1 Ninth Company, Third Battalion, Cadet Brigade, Fourth Military Medical University, Xi’an 2 Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an * Email: chenfq@ nd th st Received: May 2 , 2014; revised: May 25 , 2014; accepted: Jun. 1 , 2014 Copyright © 2014 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Abstract Noise-induced hearing loss (NIHL) is one of the most popular professional diseases across countries. The specific pathogenesis of NIHL is complicated and remains unclear. Now researchers try to understand NIHL with advanced molecular biological technology, which dives deep into gene level. This review will try to find out what researchers have found through years of re- searches. Keywords Noise-Induced Hearing Loss (Nihl), Oxidative Stress, Potassium Recycling Pathway Genes, HSP70 噪声性耳聋易感基因研究进展 1 2* 陈新焰 ，陈福权 1第四军医大学学员旅三营九连，西安 2第四军医大学西京医院耳鼻咽喉头颈外科，西安 * Email: chenfq@ 收稿日期：2014年5月2 日；修回日期：2014年5月25 日；录用日期：2014年6月1 日 *通讯作者。 5 噪声性耳聋易感基因研究进展 摘 要 噪声性耳聋(noise-induced hearing loss, NIHL)是世界上最流