骨髓增殖性肿瘤.ppt

Diagnostic Criteria for PMF → Diagnosis of primary myelofibrosis (PMF) requires meeting all three major criteria and two minor criteria ← Teferri et al. Leukemia (2008) 22, 14–22 2008 WHO Diagnostic Criteria for Primary Myelofibrosis Major: 1. Megakaryocytic proliferation and atypia with either reticulin or collagen fibrosis or If no fibrosis, mekakaryocytic expansion must be assn. w/ increased BM cellularity 2. Does not meet WHO criteria for CML, PV, MDS, or other myeloid neoplasm 3. Demons