生物多样性分析基础.pdf

演讲人 ：李欢 What is Bioinformatics? Bioinformatics is the field of science in which biology, computer science, and information technology merge into a single discipline. Introduction to Bioinformatics Development of methods algorithms to organize, integrate, analyze and interpret biological and biomedical data Study of the inherent structure flow of biological information Goals of bioinformatics: – Identify patterns – Classify – Make predictions – Create models – Better utilize existing knowledge Biodiversity species species diversity richness Biologists most often define biodiversity as the totality of genes, species, and ecosystems of a region.An advantage of this definition is that it seems to describe most circumstances and presents a unified view of the traditional three levels at which biological variety has been identified: species diversity ecosystem diversity genetic diversity 常用分析软件平台 • A single piece of open-source, expandable software • Offers a suite of tools from processing raw reads to community analysis • Includes many popular software algorithms • Command-line based 2013/10/22 Quantitative Insights Into Microbial Ecology comparison and analysis of microbial communities high-throughput amplicon sequencing data ~~ a variety of platforms QIIME takes users from their raw sequencing output through initial analyses such as ： OTU picking, taxonomic assignment construction of phylogenetic trees through downstream statistical analysis visualization production of publication-quality graphics. Raw Data 基础分析流程 Trim 数据预处理 Unique