抽吸导管联合冠脉内替罗非班在直接PCI中的临床疗效观察艾辉.pptVIP

抽吸导管联合冠脉内替罗非班在直接PCI中的临床疗效观察 首都医科大学附属北京安贞医院抢救中心 艾辉 王春梅 朱小玲 等 摘 要 直接PCI VS 溶栓 直接PCI中“无复流”/ “慢血流” 研究方法 观察指标 结 果：两组基线资料 结 果：术中情况 结 果： TnI、CK-MB峰值及ST段回落率 结 果： 住院期间事件发生率 讨论：无复流/慢血流 讨论 讨 论：本研究结果显示 里程碑研究——TAPAS试验 替罗非班 结 论 局限性 本研究为单中心的回顾性研究 仅显示了血栓抽吸联合冠脉内推注替罗非班的近期疗效 远期效果及对于患者长期预后的影响有待于进一步大规模的临床研究加以证实。 Effect of thrombus aspiration combinded with Tirofiban in primary percutaneous coronary intervention for acute myocardial infarction Department of Emergency Medcine Capital University of Medical Sciences affitiated Beijing Anzhen Hospital AI Hui, ZHU Xiaoling, WANG Chunmei,et al Effect of thrombus aspiration combinded with Tirofiban in primary percutaneous coronary intervention for acute myocardial infarction Primary PCI VS Thrombolysis No-flow/slow-flow in Primary PCI Method Observation index  Result： Baseline Result：Angiographic and procedural outcomes Result： TnI peak、CK-MB peak and  ST segment resolution Result： Mace in hospital Discussion：no-reflow/slow flow Discussion Discussion Landmark research —TAPAS trail Tirofiban Conclution Limitation Objective Methods Results Conclusion To evaluate the effect of thrombus aspiration (AT) combined with Tirofiban during primary PCI in patients with acute myocardial infarction. To select the patients with AMI who undergoing primary PCI and receiving AT combined with Tirofiban (n=113) were enrolled in study group, and those who only received routine PCI (n=249)were in control group In the study group, stent were directly implanted and TIMI flow grade 3 was obtained were all superior to the control group, and significant difference of no-reflow /slow flow was observed . There was lower peak serum CK-MB , TnI , faster ST segment resolution in the study group . The heart failure, re-infarction and mortality in hospital were decreased in the study group . Application of AT combined with Tirofiban in patients with AMI was effecti