RAS抑制剂的联合治疗.pptVIP

RAAS抑制剂的联合治疗浙江大学心血管病研究所浙江大学医学院附属第一医院胡申江 ;ACE抑制剂和ARB：RAAS抑制;心脏保护的联合治疗证据;VALSARTAN HEART FAILURE TRIAL 缬沙坦治疗心力衰竭试验;0; 研究回顾; 代文? 降低所有原因病死率与发病率联合终点13.2%; 代文? 降低心力衰竭住院*27.5%;代文?降低所有原因病死率和病残率联合终点44%;50;;Pfeffer, McMurray, Velazquez, et al. N Engl J Med 2003;349;代文可降低心肌梗死高危患者死亡率达25%;非劣效性成立;卡托普利(n=4,909);0;CHARM-Added: Study design;CHARM-Added: Baseline characteristics by ACEI dose;CHARM-Added: Daily ACEI dose;CHARM-Added: Primary outcome of CV death or HF hospitalization;CHARM-Added: Primary outcome in patients taking a ?-blocker;Summary: CHARM-Added;ARBs 治疗心肌梗死和心力衰竭: 现今的观点;;疑问：