七氟醚与丙泊酚静脉麻醉对老年髋关节置换术患者认知功能的影响.PDFVIP

学信息2018 年5 月第31 卷第9 期 Medical Information. May. 2018. Vol. 31. No.9 物与临床 窑 物与临床窑 氟醚与丙泊酚静脉麻醉对老年髋关节置换术患者 认知功能的影响 王丹 谢婷婷 张 莉 渊宁夏回族自治区人民医院麻醉科,宁夏 银川 750021冤 摘 要 目的 比较七氟醚复合静脉麻醉与丙泊酚静脉麻醉对老年髋关节置换术患者认知功能的影响遥 方法 择期拟行髋关节 置换术老年患者60 例 采用随机数字表法分为七氟醚组和丙泊酚组,各30 例 七氟醚组常规麻醉诱导后予2.5% ~3.5%七氟醚, 丙泊酚组常规麻醉诱导后予丙泊酚静脉靶控输注 分别于术前1 d 和术后7 d 行镇静/警觉评分和简明精神状态量表评分评 患者认知功能遥 结果 丙泊酚组OAA/s 评分渊4.21 0.40冤分 高于七氟醚组渊3.98 0.35冤分 差异有统计学意义渊 约0.05冤曰术后7 d 丙泊酚组MMSE 评分尧语言能力 高于七氟醚组 差异有统计学意义渊 约0.05冤 定向力尧记忆力尧注意力和计算力尧回忆能力与七 氟醚组 差异无统计学意义渊 跃0.05冤遥 结论 丙泊酚静脉麻醉引起的术后认知功能损害低于七氟醚复合静脉麻醉 是老年患者 更为理想的麻醉方案遥 关键词 七氟醚曰丙泊酚曰镇静/警觉评分曰简明精神状态量表曰认知功能 中图分类号 R614 文献标识码 A DOI 10.3969/j .issn.1006-1959.2018.09.041 文章编号 1006-1959渊2018冤09-0133-03 Effects of Sevoflurane and Propofol Intravenous Anesthesia on Cognitive Function in Elderly Patients Undergoing Hip Replacement WANG Dan,XIE Ting-ting,ZHANG Li (Department of Anesthesiology,the Ningxia Hui Autonomous Region Peoples Hospital,Yinchuan 750021,Ningxia,China) Abstract Obj ective To compare the effects of sevoflurane combined intravenous anesthesia and propofol intravenous anesthesia on cognitive function in elderly patients undergoing hip arthroplasty. Methods 60 elderly patients undergoing hip arthroplasty were randomly divided into sevoflurane group(n=30)and propofol group(n=30).The sevoflurane group received 2.5% ~3.5% sevoflurane after induction of routine anesthesia.Propofol group was given target intravenous infusion of propofol after induction of routine anesthesia, The patientsundefined cognitive function was evaluated 1 d before operation and 7 d after operation by sedation/alertness scale and brief mental state