Ischemia-reperfusioninjury（缺血-再灌注损伤）liuJinbao.pptVIP

Ischemia-reperfusion injury (缺血-再灌注损伤)liu Jinbao Department of Pathophysiology Guangzhou Medical College 1999,10 Introduction Concept（概念）: the reestablishment of blood flow after prolonged ischemia aggravates the tissue damage. Target（对象）: heart,brain,intestine,liver,kidney,lung,pancreas,skeletal muscle,etc. Clinical phenomenon（临床现象）:bypass surgery(搭桥手术),shock treatment,organ transplantation(器官移植), thrombolysis,recovery of hearts after ischemic arrest 缺血再灌注损伤的普遍性 Governing factors of reperfusion injury （再灌注损伤影响因素） 缺血时间(Duration of ischemia) 缺血程度(Severity of ischemia) 再灌速度(Sp