老鼠胚胎发育时期示意图.pdfVIP

Theiler Stage 1 - One-cell egg Theiler Stage 1 - One-cell egg TThheeiilleerrSSttaaggee11--OOnnee--cceelllleegggg Fertilized one-cell stage egg (embryo), zona pellucida present (shown in red). 0-0.9 dpc (range 0-2.5) Scale bar in microns Theiler Stage 2 - Dividing egg Theiler Stage 2 - Dividing egg TThheeiilleerrSSttaaggee22--DDiivviiddiinnggeegggg Dividingeggstage,zonapellucidapresent(shown in red). First cleavage occurs at about 24 hours. 1 dpc (range 1-2.5) 2-4 cells. Scale bar in microns Theiler Stage 3 - Morula Theiler Stage 3 - Morula TThheeiilleerrSSttaaggee33--MMoorruullaa Four- to 16-cell stage embryos from early to fully compactedmorula.Zonapellucidapresent(shownin red). Embryos in the oviduct towards utero-tubal junction. 2 dpc (range 1-3.5) 4-16 cells. All scale bars in microns. Theiler Stage 4 - Blastocyst (ICM apparent) Theiler Stage 4 - Blastocyst (ICM apparent) TThheeiilleerrSSttaaggee44--BBllaassttooccyysstt((IICCMMaappppaarreenntt)) Embryo progresses from morula to the blastocyst stillwithinthezonapellucida(showninred).Thereis early evidence of the blastocoelic cavity. 3 dpc (range 2-4) 16-40 compacted cells. All scale bars in microns. In the blastocyst stage (zona-intact) there is a distinct inner cell mass and an outer layer of trophectoderm cells. Usually located in the uterine lumen. Theiler Stage 5 - Blastocyst (zona-free) Theiler Stage 5 - Blastocyst (zona-free) TThheeiilleerrSSttaag