青年结直肠癌的临床病理特征及预后-中国科技论文在线.PDFVIP

2002年12月第 5卷第4期 Chin J Gaslrolnlesl Surg，December 2002，Vol 5，No．4 · 论 著 · 青年结直肠癌的临床病理特征及预后 汪建平 王磊 杨祖立 黄奕华 董文广 覃建章 詹文华 【摘要】 目的 探讨青年人结直肠癌的临床病理特征和预后。方法 回顾性分析1994年7月 至2001年7月收治的l5l例小于40岁的结直肠癌患者(青年组)的临床病理和随访资料，与同时期 收治的465例65岁及其以上(老年组)的结直肠癌患者的临床资料进行对比。结果 结直肠癌青年 组与老年组患者在家族史、肿瘤大小、组织分型、分化程度等方面差异有显著性意义(P0．05)，而 在肿瘤的病理分期、侵袭程度、淋巴结转移等方面差异无显著性意义(P0．05)。青年组和老年组术 后5年生存率分别为54．6％和53．1％，差异无显著性意义(P0．05)。结论 结直肠癌患者青年组 和老年组在病理分期和预后方面无差异，因此，年龄不是决定结直肠癌预后的因素。 【关键词】 结直肠肿瘤；青年；临床病理；预后 Clinicopathological characteristics and prognosis of patients younger than 40 years with colorectal cancer WANG Jianping,WANG Lei，YANG Zuli，et o2．Department ofGastrointestinopancreatic Surgery, The Fimt Affiliated Hospital，Sun Yat·sen University，Guangzhou 510080，China 【Abstract】 Objective To investigate the clinicopathological features and prognosis of patients younger than 40 years with eoloreetal cancer．Methods The clinicopatholo百cal and follow·up data of 1 5 1 patients younger than 40 years with eoloreetal cancer from July， 1994 to July，2001 were retrospectively reviewed，and compared with that of 465 patients aged 65 and older than 65 years with eoloreetal cancer． Results Significant differences were found in family history，tumor size，histologic type and differentiation grade．There were no significant difference in Dukes stage， infiltration depth，nodal metastasis were found between these two groups．The 5-year survival rates of younger group and older group were 54．56％ and 53．1 1％ respectively(P0．05)．Conclusion There ale no significant differences in Duke S stage and survival rate between two groups，and the age is not the prognostic factor for eoloreetal cancer． 【Key words J Coloreetal neoplasms；Youth；Clinical pathology；Prognosis 结直肠癌多见于中老年人，青年人的发病率较 1 2