门冬胰岛素联合甘精胰岛素治疗儿童1型糖尿病的临床效果分析.docxVIP

门冬胰岛素联合甘精胰岛素治疗儿童1型糖尿病的临床效果分析 　　[摘要] 目的 研究分析对儿童I型糖尿病患者采用门冬胰岛素与甘精胰岛素相结合的临床治疗效果。方法 选取该院XX年12月―XX年12月接收的54例儿童I型糖尿病患者，通过应用计算机产生随机数字，分为联合组和参照组，其中参照组为27例，予以门冬胰岛素单一治疗，联合组为27例，予以门冬胰岛素与甘精胰岛素结合治疗，比较两组治疗前后空腹血糖、餐后2 h血糖以及糖化血红蛋白、甘油三酯指标变化情况。 结果 统计数据并比较分析，治疗前，两组各临床治疗指标变化差异无统计学意义；治疗后，联合组空腹血糖值、餐后2 h血糖值以及糖化血红蛋白、甘油三酯临床指标均获得十分显著的改善，且要优于参照组，差异有统计学意义。 结论 对儿童I型糖尿病患者应用?T冬胰岛素与甘精胰岛素联合治疗方案相结合，治疗效果显著，值得推广。　　[关键词] 门冬胰岛素；甘精胰岛素；儿童I型糖尿病　　[中图分类号] [文献标识码] A [文章编号] 1672--0065-02　　[Abstract] Objective To research and analyze the clinical effect of insulin aspartate combined with insulin glargine in treatment of children with type I diabetes. Methods 54 cases of children with type I diabetes admitted and treated in our hospital from December XX to December XX were selected and randomly divided into two groups， with 27 cases in each， the control group adopted the single treatment of insulin aspartate， while the combined group were treated with insulin aspartate combined with insulin glargine， and the fasting blood glucose， postprandial 2 h blood glucose， glycosylated hemoglobin and triglyceride were compared before and after treatment. Results The statistical data showed that the differences in the changes of clinical treatment indicators between the two groups were not obvious， after treatment， the fasting blood glucose value， postprandial 2 h blood glucose value and glycosylated hemoglobin and triglyceride could obtain a very obvious effect， and the improvement effect was better than that in the control group， and the differences were statistically significant. Conclusion The application of insulin aspartate combined with insulin glargine in treatment of children with type I diabetes has an obvious treatment effect， which is worth promotion.　　[Key words] Insulin aspartate； Insulin glargine； Children with type I diabetes　　儿童I型糖尿病患者通常是由于其自身的糖代谢紊乱、蛋白质代谢紊乱以及脂肪代谢问题造成的，一般会表现出酮症酸中毒症状，患者会出现恶心呕吐、呼吸急促以及嗜睡、昏迷等临床表现，同时患者还会表现出视网膜病变以及白内障、神经病变等症状，对患者的身体健康以及生命安全造成严重的威胁，因此对儿童I型糖尿病患者及时给予科学、合理的治疗方案，就显得十分重要。根据目前临床医学研