单细胞光纳米光电检技术简介.ppt

江苏瑞明生物科技有限公司 单细胞纳米光电同步检测技术 在生命科学领域的应用 新的应用？ 1 2 3 4 单细胞技术 研究案例 单细胞光电检测技术 5 We all start out as a single totipotent cell that is programmed to produce a multicellular organism. How do individual cells make those complex developmental switches? How do single cells within a tissue or organ differ? how do they coordinate their actions or go astray in a disease process? Why do seemingly identical cells respond differently to a drug? Why single cell? Single-nucleus sequencing 癌细胞：复杂的亚细胞群，意味着复杂的基因组以及复杂的拷贝数变异（CNV），单细胞测序让这些“复杂”变得“简单化”，从而“清晰化”。 通过对来自于同一基因组背景的100个单细胞分别测序，鉴定到了一个原始的基因扩增。 (Nichol