牙周膜胶原纤维组织切片的显微图像配准-计算机工程与应用.PDF

Computer Engineering and Applications 计算机工程与应用 2012 ，48 （19） 167 牙周膜胶原纤维组织切片的显微图像配准 1，2 2 3 1 杨 玲 ，孙翠刚 ，王中科 ，饶妮妮 1，2 2 3 1 YANG Ling , SUN Cuigang , WANG Zhongke , RAO Nini 1.电子科技大学 生命科学与技术学院，成都 610054 2.成都信息工程学院 电子工程学院，成都 610225 3.成都信息工程学院 网络工程学院，成都 610225 1.School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China 2.College of Electronic Engineering, Chengdu University of Information Technology, Chengdu 610225, China 3.College of Networks Engineering, Chengdu University of Information Technology, Chengdu 610225, China YANG Ling, SUN Cuigang, WANG Zhongke, et al. Micrographs image registration of collagen fibers slices in periodontal ligament. Computer Engineering and Applications, 2012, 48 （19）：167-170. Abstract ：For it is very sensitive to the strength and direction in the production process of paraffin serial sections, it easily results in periodontal ligament tissue deformation and spatial displacement. This paper proposes an efficient image registration method to help reconstruct its spatial structure. On the basis of the Masson staining paraffin sec- tions of rabbit Perio Dontal Ligament （PDL ）, the serial section images of PDL are obtained in the high optical microscope. And a new registration method that is combined rigid registration in 2D based on regular step gradient descent optimizer and non-rigid registration based on the symmetric log-domain diffeomorphic Demons algorithm is introduced and used for image cascade registration of slice images. The results show that the symmetric log-domain diffeomorphic Demons algorithm is better than Finite Element Method （FEM ）registering each slice with 3.1% average processing time of FEM, and 89% average MSE of FEM. Key words ：micrographs image; collagen fiber; image registration 摘 要：针对牙周膜