磺基脱氧葡萄糖甘油二酯对脂质体的稳定作用3.PDF

第14卷 第3期 中 国 生 物 化 学 与 分 子 生 物 学 报 V o l14,N o 3 1998年6月 Ch inese Jou rnal of B iochem istry and M o lecu lar B io logy Jun. 1998　 研究简报 6- 磺基脱氧葡萄糖甘油二酯对脂质体的稳定作用 韩　兴　李　刚 (北京医科大学生物物理系, 北京100083) The Stabiliz ing Effect of Sulphoquinovosyl d iacyl- glycerol on L iposom es 　 H an X ing L i Gang ( , , 100083) D ep artm ent of B iop hy sics B eij ing M ed ical U niversity B eij ing Abstract　L ipo som e is w idely u sed in basic researches as a m odel system fo r b io logical m em , . b rane and it is a k ind of comm ercial p roduct of increasing dem ands T herefo re lipo som e sta . b ility is an im po rtan t issue R epo rted here is a study on the stab ilizing effect of su lpho qu inovo syl diacylglycero l on lipo som es of differen t types by u sing fluo rescence dye dequench ing m ethod. Su lphoqu inovo syl diacylglycero l is found to have a m arked stab ilizing effect on , low pH sen sitive lipo som es com po sed of dio leoyl pho sphatidylethano lam ine o leic acid o r , 2+ m onogalacto syl diacylglycero l o leic acid and on Ca sen sitive lipo som es com po sed of cardi . o lip in dim yristoyl pho sphatidyl cho l