多孔Ta的制备及其作为骨植入材料的应用进展.PDF

第53 卷 第10 期 Vol.53 No. 10 2017 年10 月 ACTA METALLURGICA SINICA Oct. 2017 多孔Ta 的制备及其作为骨植入材料的应用进展 赵德伟 李军雷 (大连大学附属中山医院骨科医学研究中心 大连 116001) 摘 要 多孔Ta 金属是近二十年发展起来的一种具有良好生物相容性、优异的综合力学特性的骨植入材料，具 备弹性模量与骨组织相匹配、高摩擦系数提高植入体植入初期稳定性、诱导新生骨组织长入提高植入体长期 稳定性等方面优势，在临床上获得广泛应用。本文从多孔Ta 金属作为骨植入材料的应用背景、优势、制备方 法、生物学性能以及临床应用情况等方面，阐述了多孔Ta 金属作为骨植入材料的研究现状及最新动态，并对其 发展前景进行了展望。 关键词 多孔Ta，骨植入材料，骨小梁金属 中图分类号 R318.08 文章编号 0412-1961(2017) 10-1303-08 Fabrication of the Porous Tantalum and Its Current Status Used as Orthopedics Implants Materials ZHAO Dewei, LI Junlei Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China Correspondent: ZHAO Dewei, professor, Tel: (0411 E-mail: gksys@126.com Supported by National Science and Technology Pillar Program of China (No.2012BAI 17B02), National Key Re- search and Development Program of China (No.2016YFC 1102000), China Postdoctoral Science Foundation (No. 171479) and Affiliated Zhongshan Hospital of Dalian University (No.DLDXZSYY- DK201701) Manuscript received 2017-06-30, in revised form 2017-08-09 ABSTRACT Porous tantalum (PT) is an orthopedics implant material that has been developed rapidly in recent decades. PT exhibits excellent biocompatibility, outstanding comprehensive mechanical proper- ties, initial stability originated from their high friction factor and long term stability from their good osteoin- duction, which make it widely applied in clinical practice. In this review, state of the arts and recent deve- lop