利奈唑胺相关小板减少.pptVIP

* * * * * 利奈唑胺相关性血小板减少 陈 超 解放军总医院 药品保障中心 临床药学室 MRSA VRE VRSA BACKGROUND 万古霉素 vancomycin 利奈唑胺 linezolid Antimicrobial resistance in China has become a serious healthcare problem, with high resistance rates of most common bacteria to clinically important antimicrobial agents. Methicillin-resistant S. aureus, ESBL-producing Enterobacteriaceae and carbapenem-resistant Acinetobacter baumannii represent more than 50% of microbial isolates. Linezolid oxazolidinone antibiotics 2000 FDA 2007 SFDA unique mechanism of the antibacterial action inhibition of protein synthesis in bacter