课件：肾脏活体组织病理检查的诊断意义.ppt

IgA肾病 Stage Proteinuria Glemerular filtration Pathology I normal normal - hyperfiltration normal - mild diffuse lesion II microalbuminuria normal - hyperfiltration normal - moderate diffuse lesionwith occasional nodular lesion IIIA persistent normal moderate diffuse lesionwith frequent nodular lesion IIIB persistent (1g=day) low (=60 ml/min) severe diffuse lesionwith frequent nodular lesion IV persistent very low end-stage kidney V Hemodialysis Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy Diabetic Nephropathy 后面内容直接删除就行 资料可以编辑修改使用 资料可以编辑修改使用 资料仅供参考，实际情况实际分析 主要经营：课件设计，文档制作，网络软件设计、图文设计制作、发布广告等 秉着以优质的服务对待每一位客户，做到让客户满意！ 致力于数据挖掘，合同简历、论文写作、PPT设计、计划书、策划案、学习课件、各类模板等方方面面，打造全网一站式需求 * * * 膜增生性肾炎Ⅰ型 膜增生性肾炎Ⅰ型 膜增生性肾炎Ⅰ型 Moving from urinary space to capillary limen there is the urinary space, effaced foot processes, the lamina lucida externa, lamina densa, the subendothelial electron dense deposits which are lying adjacent to the little fingers of mesangial cytoplasm that have extended into the subendothelial zone, new basement membrane material, and endothelial cell with pores. 膜增生性肾炎Ⅰ型 This electron micrograph shows the urinary space, the effaced foot processes, the original basement membrane, and conspicuous subendothelial deposits. 膜增生性肾炎Ⅰ型 Immunofluorescence microscopy (slide 47) typically demonstrates peripheral granular or band-like staining that may outline the hypersegmentation. In many patients with type I MPGN, C3 will be the most conspicuous component in the deposits, especially in the idiopathic childhood variant. Patients with MPGN often have hypocomplementemia and a circulating autoantibody called C3 nephritic factor, which binds to the C3 convertase of the alternative pathway. 膜增生性肾炎Ⅰ型 Hepatitis C infection is a common cause for type I membranoproliferative glomerulonephritis, especially if it is accompanied by mixed cryoglobulinemia. W