上海交通大学医学院2012级研究生文献导读相关知识介绍.pptVIP

An Epigenetic Switch Involving NF-kB,Lin28, Let-7 microRNA, and IL6 LinksInflammation to Cell Transformation Cell 139, 693–706, November 13, 2009 Virus Associated tumors DNA viruses Epstein-Barr Burkitt’s lymphoma Nasopharyngeal cancer Hepatitis B Liver cancer Papilloma virus Benign warts Cervical cancer RNA viruses (HIV-1) Kaposi’s sarcoma (HTLV-1) Adult T-cell leukemia HTLV-2 Hairy cell leukemia HTLV-5 Cutaneous T-cell leukemia Cell derived mediators 炎性介质的种类作用 血管扩张： 组胺、缓激肽、PGE2、PGD2、PGF2、PGh、NO 血管通透性增高： 组胺、缓激肽、C3a、C5a、LTC4 LTD4、LTE4、PAF、P物