左炔诺孕酮宫内缓释系统预防子宫内膜异位症.docxVIP

左烘诺孕酮宫内缓释系统预防子宫内膜异位症 道县人民医院 湖南道县425300 【摘 要】目的探讨左烘诺孕酮宫内缓释系统在子宫内膜异位症临床治疗中的 效果。方法 收集2015年3月至2016年3月来我院接受子宫内膜异位症保守 性手术治疗患者60例，采用随机数字法分为两组，对照组(n=30)术后口服孕 三烯酮进行巩固治疗，观察组(n=30)术后使用左烘诺孕酮宫内缓释系统进行巩 固治疗，比较两组患者术后疼痛程度、血清CA125水平、子宫内膜异位症复发 情况和不良反应发生情况。结果观察组患者术后3月疼痛VAS评分为 2.48plusmn;0.93 分，对照组为 4.66plusmn;1.35 分，Plt;0.05；观察组患者术 后6月患者VAS评分为1.75plusmn;0.63分,对照组为4.13plusmn;1.12分, Plt;0.05；观察组患者术后6月CA125水平为23.58plusmn;10.55 U/mL,对照 组为41.27plusmn;11.24 U/mL, Plt;0.05；观察组患者子宫内膜异位症复发率为 6.67%,对照组为30.00%, Plt;0.05；观察组患者不良反应发牛率明显低于对照 组，Pt;0.05o结论左烘诺孕酮宫内缓释系统可有效改善子宫内膜异位症保守 性手术的巩固治疗效果，对于改善患者术后疼痛程度、降低子宫内膜异位症术后 复发率均具有积极作用，且不良反应较少，安全性良好，值得推广应用。 【关键词】子宫内膜异位症；孕三烯酮；左烘诺孕酮；宫内缓释系统 [Abstract] objective to evaluate the left acetyle ne conn aught progester one intrauterine slow-release system in the treatment of endometriosis clinical effect. Methods collected in March 2015 to March 2015 to our hospital in patients with endometriosis conservative surgical treatment of 60 cases, can be divided into two groups by random number method, the control group (n = 30) postoperative oral pregnant three ketene consolidation therapy, observation group (n 二 30) postoperative left acetyle ne corm aught progester one in trauteri ne slow-release system for consolidating treatment, compared two groups of patients postoperative pain degree, serum CA125 level, recurrenee of endometriosis and adverse reactions occur. Results observation group of patients with postoperative pain VAS score was 2.48 + /-2.48 in March, 4.66 + /-l.35 points, the control group (P lt; 0.05； Observation group of patients of postoperative patients with June VAS score was 1.75 + /-0.63 points, 4.13 + /-l.12 points, the control group (P lt; 0.05； Observation group of patients with postoperative CA125 levels in June 23.58 + 10.55 U/mL, 41.27 + 11.24 U/mL, the control group (P lt; 0.05； Observation group of patients with endometriosis recurrenee rate was 6.67%, 30.00%, the control group (P lt; 0.05； Observation group of patients significantly lower than