二甲硅油散在上消化道内镜检查中的作用(精).docVIP

二甲硅油散在上消化道内镜检查中的作用 武育卫冯霞彭贵勇李向红 （第三军医大学西南医院全军消化病研究所重庆 400038） 摘要 目的 评价二甲硅油散在上消化道内镜检查中的临床价值。方法对行上消化道内镜检查患者随机分成两组，实验组检查术前15-20分钟口服二甲硅油散溶液30-50ml ，对照组直接行内镜检查。根据内镜下消化道黏膜视野清晰程度分成ABCD四级，并行统计学处理。对两组病变发现率和幽门螺杆菌检出率进行比较。结果二甲硅油散组内镜下食管、胃底、胃体、胃角、胃窦和十二指肠黏膜视野清晰度均明显高于对照组相应部位。二甲硅油散组发现病变直径≤0.5cm的微小病变数量明显多于对照组，而直径＞0.5cm的病变数量无显著性差别。二甲硅油散组和对照组对幽门螺杆菌检出率无统计学差异。结论二甲硅油散能够提高上消化道黏膜视野清晰度，有利于内镜医师观察和发现病变，特别对微小病变有重要价值。 关键词 二甲硅油散；上消化道；内镜检查 Value of Simethicone powder in superior gastrointestinal endoscopy WU Yu-wei, FENG Xia, PENG Gui-yong, LI Xiang-hong. (Gastroenterology Research Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China) Abstract Objective To evaluate the clinical value of simethicone powder in superior gastrointestinal endoscopy. Methods Patients who underwent gastroscopy were randomly divided into two groups. Experiment group received simethicone powder solution 30-50ml before the endoscopy about 15 minutes, control group was examined directly. The sharpness of the endoscopic eyeshot was recorded A 、B、C、D. The discoverable rate of lesions and Helicobacter pylori were contrasted. Results The sharpness extent of simethicone powder group including oesophagus and gastric fundus and gastric body and gastric horn and gastric antrum and duodenum was obviously higher than that of the control group. Amount of the minimal lesion (diameter≤0.5cm) in simethicone powder group exceeded that of the control group, but amount of the lesions (diameter＞0.5cm) was not differential in two groups. And detection rate of Helicobacter pylori in two groups was not different in statistics. Conclusion Simethicone powder can improve the sharpness of the endoscopic eyeshot in upper gastrointestinal tract, which profits endoscopic doctor to observe and discover lesions, and which has important value especially in observing the minimal lesions. Key words Simethicone powder; Upper gastrointestinal tract; Endoscopy 内镜检查是发现和确诊上消化道疾病最准确方法。但是，在内镜检查过程中，会遇到食管、胃及十二指肠粘膜表面覆盖大量泡沫和粘液情况，导致视