密码子偏性分析方法及相关研究进展.pdfVIP

HEREDITAS (Beijing) 2007 4 , 29(4): 420426 ISSN 0253-9772 DOI: 10.1360/yc-007-0420 1,2 2 1 2 2 , , , , 1. , 110161; 2. , 102206 : , DNA , ; , , , : ; ; The analysis method and progress in the study of codon bias 1,2 2 1 2 2 WU Xian-Ming , WU Song-Feng , REN Da-Ming , ZHU Yun-Ping , HE Fu-Chu 1. College of biological science and technology, Shenyang agriculture university, Shenyang 110161, China; 2. Beijing Proteome Research Center, Beijing 102206, China Abstract: Codon bias refers to the nonrandom usage of synonymous codons for encoding amino acids in organisms. As it is related to the carrier molecular of genetic information (DNA) and functional molecular (protein) of life, this phenomenon implicates important biological sense. In this review, we summarize the basic theories and analysis methods about codon bias; and present the softwares and websites which are usually used for codon usage analysis. The related fields about codon bias and the research progress are also introduced. Keywords: codon bias; gene expression; genetic codon , (optimal codon), DNAmRNA, (codon bias)20 70 , , , [1], , 6 , , , , ,